Casp12tm1Dgen
Targeted Allele Detail
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| Nomenclature |
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Symbol:
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Casp12tm1Dgen
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Name:
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caspase 12;
targeted mutation 1, Deltagen
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MGI ID: |
MGI:3604507 |
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Gene:
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Casp12
Location:
Chr9:5345430-5373032 bp, + strand
Genetic Position: Chr9,
2.46 cM, cytoband A1
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:101679
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Parent Cell Line:
| E14 (ES Cell) |
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Strain of Origin:
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129P2/OlaHsd
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Mutation
description |
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Allele
Type: | |
Targeted (Reporter) |
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Mutation: | |
Disruption caused by insertion of vector |
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Mutation details: A bacterial lacZ gene was inserted into the gene such that the endogenous gene promoter drives expression of beta-galactosidase. RNA transcripts are detectable in: brain, cerebellum, brainstem, spinal cord, eye, Harderian gland, heart, lung, liver, pancreas, kidney, spleen, thymus, lymph nodes, bone marrow, skin, gallbladder, urinary bladder, pituitary gland, adrenal gland, salivary gland, skeletal muscle, tongue, stomach, small intestine, large intestine, cecum, testis, epididymis, seminal vesicle, coagulating gland, prostate gland, ovary, uterus and white fat. LacZ (beta-galactosidase) expression is detectable in brain, spinal cord, sciatic nerve, Harderian glands, spleen, lymph nodes, aorta, heart, lung, pancreas, kidney, urinary bladder, trachea, larynx, thyroid gland, parathyroid gland, adrenal glands, salivary glands, tongue, male and female reproductive systems. In many tissues, lacZ expression is detectable in blood vessels and ganglia.
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Notes |
See also,
data
as provided by Deltagen, Inc.
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| References |
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Original: |
J:101679
Deltagen Inc,
"NIH initiative supporting placement of Deltagen, Inc. mice into public repositories"
MGI Direct Data Submission 2005;():
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All: |
1 reference(s)
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Analysis Tools
