Clca5tm1Dgen
Targeted Allele Detail
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| Nomenclature |
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Symbol:
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Clca5tm1Dgen
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Name:
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chloride channel calcium activated 5;
targeted mutation 1, Deltagen
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MGI ID: |
MGI:3604504 |
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Gene:
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Clca5
Location:
Chr3:145070265-145099041 bp, - strand
Genetic Position: Chr3,
69.31 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:101679
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Parent Cell Line:
| E14 (ES Cell) |
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Strain of Origin:
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129P2/OlaHsd
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Mutation
description |
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Allele
Type: | |
Targeted (Reporter) |
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Mutation: | |
Disruption caused by insertion of vector |
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Mutation details: A bacterial lacZ gene was inserted into the gene such that the endogenous gene promoter drives expression of beta-galactosidase. RT-PCR analysis detects a high level of gene transcript in skin, urinary bladder, tongue and uterus, moderate levels in eye, pancreas, thymus, gallbladder, stomach, epididymis, seminal vesicle, prostate gland, ovary and white fat, and low levels in olfactory bulb, Harderian glands, heart, lung, kidney, spleen, lymph nodes, adrenal gland, salivary gland, skeletal muscle, small intestine, large intestine, cecum, testis and coagulating gland. However, beta-galactosidase expression from this allele is detectable in only in epithelium in the urinary bladder, trachea and skin and in tracheal cartilage as well as in a few spermatogenic cells in the testis and stromal cells in the ovary. A small piece of tissue adjacent to the heart also showed staining.
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Notes |
See also,
data
as provided by Deltagen, Inc.
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| References |
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Original: |
J:101679
Deltagen Inc,
"NIH initiative supporting placement of Deltagen, Inc. mice into public repositories"
MGI Direct Data Submission 2005;():
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All: |
1 reference(s)
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Analysis Tools
