Frzbtm1Dgen
Targeted Allele Detail
|
|
| Nomenclature |
|
Symbol:
|
Frzbtm1Dgen
|
|
Name:
|
frizzled-related protein;
targeted mutation 1, Deltagen
|
|
MGI ID: |
MGI:3604496 |
|
Gene:
|
Frzb
Location:
Chr2:80411970-80447625 bp, - strand
Genetic Position: Chr2,
48.13 cM
|
|
Mutation
origin |
|
Germline Transmission:
|
Earliest citation of germline transmission:
J:101679
|
|
Parent Cell Line:
| E14 (ES Cell) |
|
Strain of Origin:
|
129P2/OlaHsd
|
|
Mutation
description |
|
Allele
Type: | |
Targeted (Reporter) |
|
Mutation: | |
Disruption caused by insertion of vector |
| |
|
Mutation details: A bacterial lacZ gene was inserted into the gene such that the endogenous gene promoter drives expression of beta-galactosidase. RT-PCR analysis detects a high level of gene transcript in the whole brain, olfactory bulb, kidney, skeletal muscle and testis and low levels in cortex, subcortical region, cerebellum, brainstem, spinal cord, eye, heart, liver, pancreas, spleen, thymus, lymph nodes, skin, gallbladder, urinary bladder, pituitary gland, adrenal gland, salivary gland, tongue, epididymis, seminal vesicle, coagulating gland, prostate gland, ovary and uterus. Beta-galactosidase expression from this allele is detectable in brain. Strong staining was observed in olfactory bulb. Staining was also observed in regions of hypothalamus and thalamus. On coronal sections of cerebrum, moderate expression was detected in the ventral region of the third ventricle.
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
|
Notes |
See also,
data
as provided by Deltagen, Inc.
|
| References |
|
Original: |
J:101679
Deltagen Inc,
"NIH initiative supporting placement of Deltagen, Inc. mice into public repositories"
MGI Direct Data Submission 2005;():
|
|
All: |
1 reference(s)
|
|
|
Analysis Tools
