Adcy3tm1Dgen
Targeted Allele Detail
|
|
| Nomenclature |
|
Symbol:
|
Adcy3tm1Dgen
|
|
Name:
|
adenylate cyclase 3;
targeted mutation 1, Deltagen
|
|
MGI ID: |
MGI:3604495 |
|
Gene:
|
Adcy3
Location:
Chr12:4133103-4213525 bp, + strand
Genetic Position: Chr12,
1.99 cM, cytoband A-B
|
|
Mutation origin |
|
Mutant Cell Line:
| 4446 (Deltagen) |
|
Germline Transmission:
|
Earliest citation of germline transmission:
J:101679
|
|
Parent Cell Line:
| E14 (ES Cell) |
|
Strain of Origin:
|
129P2/OlaHsd
|
|
Mutation description |
|
Allele
Type: | |
Targeted (Reporter) |
|
Mutation: | |
Insertion |
| |
|
Mutation details: A bacterial lacZ gene was inserted into the gene such that the endogenous gene promoter drives expression of beta-galactosidase. RNA transcripts are detectable in all tissues analyzed. LacZ (beta-galactosidase) expression is detectable in brain, Harderian glands, aorta, heart, lung, kidney, urinary bladder, salivary glands, tongue, external ear, male and female reproductive systems. In many of the tissues with detectable expression, lacZ expression is detectable in blood vessels.
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
|
Notes |
See also,
data
as provided by Deltagen, Inc.
|
| References |
|
Original: |
J:101679
Deltagen Inc,
"NIH initiative supporting placement of Deltagen, Inc. mice into public repositories"
MGI Direct Data Submission 2005;():
|
|
All: |
1 reference(s)
|
|
|