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| Nomenclature |
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Symbol:
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Gng7tm1Lex
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Name:
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guanine nucleotide binding protein (G protein), gamma 7;
targeted mutation 1, Lexicon Genetics
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MGI ID: |
MGI:3604392 |
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Synonyms: |
Gng7-, Gng7tm1Rbs |
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Gene:
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Gng7
Location:
Chr10:80948624-81014945 bp, - strand
Genetic Position: Chr10,
39.72 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:81988
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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129S/SvEvBrd
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutation: | |
Not Specified |
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Mutation details: Coding exons 1 and 2 were targeted by homologous recombination. Neither transcript nor protein was detected in homozygous mutant brain tissue by RT-PCR and Western blot analyses. (J:81988, J:103485)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Notes |
Phenotypic Similarity to Human Syndrome: epilepsy (J:182775).
See also,
data
as provided by Lexicon Genetics, Inc.
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| References |
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Original: |
J:81988
Schwindinger WF et al.,
"Loss of G protein gamma 7 alters behavior and reduces striatal alpha(olf) level and cAMP production."
J Biol Chem 2003 Feb 21;278(8):6575-9
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All: |
4 reference(s)
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Analysis Tools
