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| Nomenclature |
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Symbol:
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Abca12tm1Lex
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Name:
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ATP-binding cassette, sub-family A (ABC1), member 12;
targeted mutation 1, Lexicon Genetics
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MGI ID: |
MGI:3528440 |
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Gene:
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Abca12
Location:
Chr1:71243090-71414910 bp, - strand
Genetic Position: Chr1,
35.81 cM
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Neonatal lethality and epidermal hyperkeratosis in Abca12tm1Lex/Abca12tm1Lex mice
Show the 4 image(s) involving this allele.
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:103485
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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129S/SvEvBrd
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: There is some discrepancy as to the exact exon tagged (either exon 8, 9 or 10). The dataset provided for this allele incorrectly states that exon 8 was targeted. It has subsequently been determined that exon 10 has been deleted. See references. The absence of protein expression was confirmed by western blot analysis on epidermis extracts. (J:103485, J:144062)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Notes |
See also,
data
as provided by Lexicon Genetics, Inc.
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| References |
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Original: |
J:103485
Lexicon Genetics Inc,
"NIH initiative supporting placement of Lexicon Genetics, Inc. mice into public repositories"
MGI Direct Data Submission 2005;():
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All: |
2 reference(s)
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Analysis Tools
