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| Nomenclature |
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Symbol:
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Slc27a4wrfr
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Name:
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solute carrier family 27 (fatty acid transporter), member 4;
wrinkle free
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MGI ID: |
MGI:2445864 |
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Gene:
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Slc27a4
Location:
Chr2:29658154-29673042 bp, + strand
Genetic Position: Chr2,
19.0 cM, cytoband B
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Histological analysis of the Slc27a4wrfr/Slc27a4wrfr mouse
Show the 2 image(s) involving this allele.
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Mutation
origin |
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Strain of Origin:
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(129X1/SvJ x 129S1/Sv)F1-Kitl+
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Mutation
description |
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Allele
Type: |
Spontaneous |
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Mutation: |
Transposon insertion |
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This mutation is an insertion of a B2-type murine retrotransposon into the third exon of the gene. Northern analysis failed to detect mRNA for this gene in mutant mice. (J:83282) |
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Inheritance: |
Recessive |
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Slc27a4 Mutation:
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2 strains or lines available |
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Phenotype
summary
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Phenotype Summary by Mammalian Phenotype terms
(show or
hide all annotated terms)
Genotypes are listed in the next section.
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Key:
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| hm |
homozygous |
ht |
heterozygous |
| cn |
conditional genotype |
cx |
complex: > 1 genome feature |
| tg |
involves transgenes |
ot |
other: hemizygous, indeterminate,... |
| N |
normal phenotype |
 |
expected model not found |
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Phenotypic
data by
genotype
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Phenotypic Data by Genotype
(show or
hide all phenotypic details)
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| Genotype | Allelic Composition | Genetic Background |
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  hm1
Disease Model  |
Slc27a4wrfr/Slc27a4wrfr |
involves: 129 * C57BL/6J |
Histological analysis of the Slc27a4wrfr/Slc27a4wrfr mouse lethality/prenatal-perinatal behavior/neurological digestive/alimentary system respiratory system skin/coat/nails |
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Disease
models
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| References |
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Original: |
J:83282
Moulson CL et al.,
"Cloning of wrinkle-free, a previously uncharacterized mouse mutation, reveals crucial roles for fatty acid transport protein 4 in skin and hair development."
Proc Natl Acad Sci U S A 2003 Apr 29;100(9):5274-9
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All: |
4 reference(s)
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