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| Nomenclature |
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Symbol:
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Men1tm1Rvt
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Name:
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multiple endocrine neoplasia 1;
targeted mutation 1, Rajesh V Thakker
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MGI ID: |
MGI:5461232 |
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Gene:
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Men1
Location:
Chr19:6334979-6340891 bp, + strand
Genetic Position: Chr19,
4.45 cM, cytoband A
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:191261
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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129
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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A floxed neo cassette replaced exons 1 and 2. (J:191261)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Men1 Mutation:
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10 strains or lines available |
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| References |
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Original: |
J:191261
Harding B et al.,
"Multiple endocrine neoplasia type 1 knockout mice develop parathyroid, pancreatic, pituitary and adrenal tumours with hypercalcaemia, hypophosphataemia and hypercorticosteronaemia."
Endocr Relat Cancer 2009 Dec;16(4):1313-27
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All: |
3 reference(s)
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Analysis Tools
