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| Nomenclature |
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Symbol:
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Bcs1ltm1.1Levp
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Name:
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BCS1-like (yeast);
targeted mutation 1.1, Per Leveen
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MGI ID: |
MGI:5446796 |
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Synonyms: |
Bcs1lG |
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Gene:
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Bcs1l
Location:
Chr1:74588289-74592443 bp, + strand
Genetic Position: Chr1,
38.54 cM, cytoband C3
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:189652
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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129
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Mutation
description |
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Allele
Type: | |
Targeted (knock-in) |
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Mutations: | |
Insertion, Single point mutation |
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Mutation details: Exon 2 was replaced with a modified exon 2, which contains a nucleotide substitution of A to G. Cre-mediated recombination removed the floxed neo cassette inserted upstream of the modified exon 2. (J:189652)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Bcs1l Mutation:
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2 strains or lines available |
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| References |
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Original: |
J:189652
Leveen P et al.,
"The GRACILE mutation introduced into Bcs1l causes postnatal complex III deficiency: a viable mouse model for mitochondrial hepatopathy."
Hepatology 2011 Feb;53(2):437-47
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All: |
2 reference(s)
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Analysis Tools
