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| Nomenclature |
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Symbol:
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DccTg(H2-K-Jak2*V617F)1Shmd>
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Name:
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deleted in colorectal carcinoma;
transgene insertion 1, Kazuya Shimoda
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MGI ID: |
MGI:5444031 |
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Synonyms: |
JAK2 V617F |
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Gene:
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Dcc
Location:
Chr18:71258738-72351069 bp, - strand
Genetic Position: Chr18,
45.24 cM
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Transgene
origin |
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Strain of Origin:
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(C57BL/6 x DBA/2)F1
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, gene disruption) |
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Mutation: | |
Insertion |
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Mutation details: This transgene consists of murine Jak2 with a phenylalanine for valine substitution at residue 617 under the control of the H-2Kb promoter. The transgene integrated in intron 12 of Dcc in this line. (J:130189)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Dcc Mutation:
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4 strains or lines available |
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| References |
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Original: |
J:130189
Shide K et al.,
"Development of ET, primary myelofibrosis and PV in mice expressing JAK2 V617F."
Leukemia 2008 Jan;22(1):87-95
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All: |
1 reference(s)
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Analysis Tools
