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| Nomenclature |
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Symbol:
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Sec63tm1Som
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Name:
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SEC63-like (S. cerevisiae);
targeted mutation 1, Stefan Somlo
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MGI ID: |
MGI:5442171 |
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Synonyms: |
Sec63flox |
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Gene:
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Sec63
Location:
Chr10:42761496-42832514 bp, + strand
Genetic Position: Chr10,
22.89 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:188763
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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129
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
| |
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Exon 2 was floxed and an FRT-flanked neo cassette was inserted into IVS2. (J:188763)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Sec63 Mutation:
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3 strains or lines available |
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| References |
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Original: |
J:188763
Fedeles SV et al.,
"A genetic interaction network of five genes for human polycystic kidney and liver diseases defines polycystin-1 as the central determinant of cyst formation."
Nat Genet 2011 Jul;43(7):639-47
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All: |
1 reference(s)
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Analysis Tools
