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| Nomenclature |
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Symbol:
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Xbp1tm3Glm
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Name:
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X-box binding protein 1;
targeted mutation 3, Laurie H Glimcher
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MGI ID: |
MGI:5441521 |
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Synonyms: |
XBP-1floxneo |
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Gene:
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Xbp1
Location:
Chr11:5520659-5525893 bp, + strand
Genetic Position: Chr11,
3.61 cM
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Mutation origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:131028
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Parent Cell Line:
| W4 (ES Cell) |
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Strain of Origin:
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129S6/SvEvTac
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Mutation description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: A floxed neo cassette was inserted into intron 1 and an additional loxP site was inserted into intron 2. (J:131028)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Xbp1 Mutation:
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10 strains or lines available |
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| References |
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Original: |
J:131028
Hetz C et al.,
"Unfolded protein response transcription factor XBP-1 does not influence prion replication or pathogenesis."
Proc Natl Acad Sci U S A 2008 Jan 15;105(2):757-62
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All: |
2 reference(s)
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