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| Nomenclature |
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Symbol:
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Tg(Rho*G90D*A337V)202Sie
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Name:
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transgene insertion 202, Paul A Sieving
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MGI ID: |
MGI:5441362 |
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Synonyms: |
G+ |
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Transgene:
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Tg(Rho*G90D*A337V)202Sie
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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C57BL/6 x DBA
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: The mouse sequence was mutated to replace glycine with an aspartic acid at position (G90D) and alanine with valine at position 337 (A337V). The second mutation allows for identification with the human-specific antibody. Several lines were establisehd from founders 116 and 202. Line 116 contains two to three more copies of the transgene compared with line 202. (J:188632)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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| References |
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Original: |
J:188632
Sieving PA et al.,
"Constitutive "light" adaptation in rods from G90D rhodopsin: a mechanism for human congenital nightblindness without rod cell loss."
J Neurosci 2001 Aug 1;21(15):5449-60
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All: |
2 reference(s)
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Analysis Tools
