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| Nomenclature |
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Symbol:
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Mfn2tm1.1Arte
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Name:
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mitofusin 2;
targeted mutation 1.1, TaconicArtemis
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MGI ID: |
MGI:5440839 |
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Synonyms: |
Mfn2loxP |
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Gene:
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Mfn2
Location:
Chr4:147873599-147904704 bp, - strand
Genetic Position: Chr4,
78.56 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:188337
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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Not Specified
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: A loxP site and FRT flanked neo cassette were inserted upstream of exon 5 and a loxP site was inserted downstream of exon 5 via homologous recombination. Flp mediated recombination removed the neo cassette. (J:188337)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Mfn2 Mutation:
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5 strains or lines available |
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| References |
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Original: |
J:188337
Lee S et al.,
"Mitofusin 2 is necessary for striatal axonal projections of midbrain dopamine neurons."
Hum Mol Genet 2012 Nov 15;21(22):4827-35
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All: |
1 reference(s)
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Analysis Tools
