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| Nomenclature |
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Symbol:
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Rnf43tm1Cle
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Name:
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ring finger protein 43;
targeted mutation 1, Hans Clevers
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MGI ID: |
MGI:5439364 |
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Gene:
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Rnf43
Location:
Chr11:87662722-87735539 bp, + strand
Genetic Position: Chr11,
52.17 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:186765
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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Not Specified
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: A loxP site was inserted upstream of the exons encoding the RING finger domain and a loxP site and FRT flanked neo cassette were inserted downstream of these exons via homologous recombination. (J:186765)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Rnf43 Mutation:
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2 strains or lines available |
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| References |
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Original: |
J:186765
Koo BK et al.,
"Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors."
Nature 2012 Aug 30;488(7413):665-9
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All: |
1 reference(s)
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Analysis Tools
