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| Nomenclature |
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Symbol:
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Prox1tm1.1Fuma
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Name:
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prospero-related homeobox 1;
targeted mutation 1.1, Fumio Matsuzaki
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MGI ID: |
MGI:5438824 |
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Synonyms: |
Prox1F |
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Gene:
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Prox1
Location:
Chr1:190118038-190170680 bp, - strand
Genetic Position: Chr1,
95.85 cM
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Mutation origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:187615
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Parent Cell Line:
| TT2 (ES Cell) |
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Strain of Origin:
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(C57BL/6NCrlj x CBA/JNCrlj)F1
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Mutation description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: A floxed mouse cDNA, EGFP, and FRT-flanked neo cassette replaced the coding sequence in exon 2. Flp-mediated recombination removed the neo cassette. (J:187615)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Prox1 Mutation:
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6 strains or lines available |
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| References |
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Original: |
J:187615
Iwano T et al.,
"Prox1 postmitotically defines dentate gyrus cells by specifying granule cell identity over CA3 pyramidal cell fate in the hippocampus."
Development 2012 Aug;139(16):3051-62
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All: |
1 reference(s)
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