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| Nomenclature |
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Symbol:
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Slc39a4tm2Gka
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Name:
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solute carrier family 39 (zinc transporter), member 4;
targeted mutation 2, Glen K Andrews
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MGI ID: |
MGI:5438020 |
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Synonyms: |
Zip4FX |
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Gene:
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Slc39a4
Location:
Chr15:76612385-76616852 bp, - strand
Genetic Position: Chr15,
36.16 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:187178
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Parent Cell Line:
| E14 (ES Cell) |
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Strain of Origin:
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129P2/OlaHsd
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: A loxP site and flanking XhoI restriction site were introduced in intron 5 and a loxP site and mc1-neo cassette were introduced downstream of the last exon via homologous recombination. (J:187178)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:187178
Geiser J et al.,
"A mouse model of acrodermatitis enteropathica: loss of intestine zinc transporter ZIP4 (Slc39a4) disrupts the stem cell niche and intestine integrity."
PLoS Genet 2012 Jun;8(6):e1002766
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All: |
1 reference(s)
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Analysis Tools
