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| Nomenclature |
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Symbol:
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Sox7tm1.1Dsco
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Name:
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SRY-box containing gene 7;
targeted mutation 1.1, Daryl A Scott
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MGI ID: |
MGI:5437221 |
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Gene:
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Sox7
Location:
Chr14:63943706-63950732 bp, + strand
Genetic Position: Chr14,
33.34 cM, cytoband C3
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:187416
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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129S/SvEv
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: A loxP site was inserted upstream of exon 2 and an FRT flanked neo cassette and loxP site were inserted downstream of exon 2 via homologous recombination. Recombinase mediated recombination removed exon 2 and the neo cassette. (J:187416)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Sox7 Mutation:
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3 strains or lines available |
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| References |
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Original: |
J:187416
Wat MJ et al.,
"Mouse model reveals the role of SOX7 in the development of congenital diaphragmatic hernia associated with recurrent deletions of 8p23.1."
Hum Mol Genet 2012 Sep 15;21(18):4115-25
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All: |
1 reference(s)
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Analysis Tools
