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| Nomenclature |
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Symbol:
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b2b1291Clo
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Name:
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Mutant line 1291;
Bench to Bassinet Program (B2B/CVDC), mutation 1291 Cecilia Lo
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MGI ID: |
MGI:5437085 |
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Synonyms: |
Bloonie |
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Gene:
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b2b1291Clo
Location:
unknown
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Mutant 1291-006-LA exhibits heterotaxy with levocardia and dextrogastria
Show the 10 image(s) involving this allele.
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Mutation
origin |
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Strain of Origin:
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C57BL/6J
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Mutation
description |
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Allele
Type: | |
Chemically induced (ENU) |
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Mutation: | |
Undefined |
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Mutation details: This ENU-induced mutation line was isolated in a screen at the University of Pittsburgh. More than one mutation in this line results in a discernible phenotype in a homozygous recessive screen. At least two segregating phenotype groups are identified. See b2b1291.1Clo and b2b1291.2Clo. (J:175213)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Notes |
Summative Diagnosis:
Mutant Type 1:
Cardiovascular phenotype: Heterotaxy with levocardia and dextrogastria
Noncardiovascular phenotype: Polycystic kidney disease
Mutant Type 2:
Polycystic kidney disease, duplex kidney and hydronephrosis
Phenotypic Similarity to Human Syndrome:
Mutant Type 1: Heterotaxy, Polycystic kidney disease
Mutant Type 2: Polycycstic kidney disease
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Analysis Tools
