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| Nomenclature |
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Symbol:
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b2b1146Clo
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Name:
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Mutant line 1146;
Bench to Bassinet Program (B2B/CVDC), mutation 1146 Cecilia Lo
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MGI ID: |
MGI:5437084 |
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Synonyms: |
Hanson |
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Gene:
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b2b1146Clo
Location:
unknown
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Mutant 1146-012-LA displays transposition of the great arteries (TGA) with abnormal lung lobation
Show the 24 image(s) involving this allele.
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Mutation
origin |
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Strain of Origin:
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C57BL/6J
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Mutation
description |
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Allele
Type: | |
Chemically induced (ENU) |
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Mutation: | |
Not Specified |
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This ENU-induced mutation was isolated in a screen at the University of Pittsburgh. (J:175213)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Notes |
Summative Diagnosis:
Cardiac defects: Complex congenital heart disease associate with heterotaxy, such as Taussig-Bing type double outlet right ventricle (DORV) associated with dextrocardia or dextroversion, atrioventricular septal defect (AVSD)
Noncardiac phenotype: Right and left lung isomerism, immotile/abnormal airway cilia dysmotility, kidney cysts
Phenotypic Similarity to Human Syndrome: Primary ciliary dyskinesia, Heterotaxy, Polycystic kidney disease
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