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| Nomenclature |
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Symbol:
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Fktntm1.1Kcam
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Name:
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fukutin;
targeted mutation 1.1, Kevin P Campbell
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MGI ID: |
MGI:5435571 |
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Gene:
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Fktn
Location:
Chr4:53713998-53765785 bp, + strand
Genetic Position: Chr4,
28.74 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:187144
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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129S/SvEv
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: A loxP site and an FRT flanked neo selection cassette were inserted upstream of exon 2 while a second loxP site was inserted downstream. Mice were subsequently crossed to an frt expressing strain to excise the selection cassette. (J:187144)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:187144
Beedle AM et al.,
"Mouse fukutin deletion impairs dystroglycan processing and recapitulates muscular dystrophy."
J Clin Invest 2012 Sep 4;122(9):3330-42
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All: |
1 reference(s)
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Analysis Tools
