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| Nomenclature |
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Symbol:
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Porcntm1Vdv
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Name:
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porcupine homolog (Drosophila);
targeted mutation 1, Ignatia B Van den Veyver
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MGI ID: |
MGI:5435555 |
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Synonyms: |
Porcn-ex3-7Neo-flox |
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Gene:
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Porcn
Location:
ChrX:8193848-8206525 bp, - strand
Genetic Position: ChrX,
3.7 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:186934
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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129S5/SvEvBrd
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: A loxP site was inserted upstream of exon 3 and a loxP site and FRT flanked neo cassette were inserted downstream of exon 7. (J:186934)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Porcn Mutation:
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15 strains or lines available |
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| References |
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Original: |
J:186934
Liu W et al.,
"Deletion of Porcn in mice leads to multiple developmental defects and models human focal dermal hypoplasia (Goltz syndrome)."
PLoS One 2012;7(3):e32331
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All: |
1 reference(s)
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Analysis Tools
