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| Nomenclature |
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Symbol:
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Tg(Thy1-SNCA)61Ema
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Name:
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transgene insertion 61, Eliezer Masliah
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MGI ID: |
MGI:5435401 |
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Synonyms: |
mThy-1-alpha-synuclein, mThy-1 tg |
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Transgene:
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Tg(Thy1-SNCA)61Ema
Location:
unknown
Genetic Position: ChrX,
Syntenic
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Transgene
origin |
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Strain of Origin:
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(C57BL/6 x DBA/2)F1
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: This transgene contains a human wild-type alpha synuclein fragment (nt 53-475) under the control of the mouse Thy1 promoter. Lines 61 was generated. Transgene expression is seen throughout the brain, including the basal ganglia, thalamus, substantia nigra, and brainstem. (J:137490)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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| References |
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Original: |
J:137490
Rockenstein E et al.,
"Differential neuropathological alterations in transgenic mice expressing alpha-synuclein from the platelet-derived growth factor and Thy-1 promoters."
J Neurosci Res 2002 Jun 1;68(5):568-78
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All: |
7 reference(s)
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Analysis Tools
