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| Nomenclature |
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Symbol:
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Tespa1tm1Lrgl
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Name:
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thymocyte expressed, positive selection associated 1;
targeted mutation 1, Linrong Lu
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MGI ID: |
MGI:5432877 |
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Gene:
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Tespa1
Location:
Chr10:130322852-130362642 bp, + strand
Genetic Position: Chr10,
77.85 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:186446
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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129
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: A neo cassette replaced exon 2 and 3. Western blot analysis confirmed the absence of protein expression in thymocytes. (J:186446)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Tespa1 Mutation:
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0 strains or lines available |
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| References |
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Original: |
J:186446
Wang D et al.,
"Tespa1 is involved in late thymocyte development through the regulation of TCR-mediated signaling."
Nat Immunol 2012 Jun;13(6):560-8
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All: |
1 reference(s)
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Analysis Tools
