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| Nomenclature |
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Symbol:
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Vps18tm1.1Wtao
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Name:
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vacuolar protein sorting 18 (yeast);
targeted mutation 1.1, Wufan Tao
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MGI ID: |
MGI:5431976 |
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Synonyms: |
Vsp18F |
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Gene:
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Vps18
Location:
Chr2:119288740-119298453 bp, + strand
Genetic Position: Chr2,
59.97 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:186307
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Parent Cell Line:
| W4 (ES Cell) |
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Strain of Origin:
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129S6/SvEvTac
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: Flp-mediated recombination removed the lacZ reporter gene and neo cassette. Exons 3 and 4 remain floxed. (J:186307)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Vps18 Mutation:
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4 strains or lines available |
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| References |
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Original: |
J:186307
Peng C et al.,
"Ablation of vacuole protein sorting 18 (Vps18) gene leads to neurodegeneration and impaired neuronal migration by disrupting multiple vesicle transport pathways to lysosomes."
J Biol Chem 2012 Aug 1;():
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All: |
2 reference(s)
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Analysis Tools
