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| Nomenclature |
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Symbol:
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Terttm3Rdp
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Name:
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telomerase reverse transcriptase;
targeted mutation 3, Ronald DePinho
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MGI ID: |
MGI:5431942 |
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Synonyms: |
LSL-mTert |
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Gene:
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Tert
Location:
Chr13:73627001-73649041 bp, + strand
Genetic Position: Chr13,
40.12 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:186105
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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Not Specified
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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A floxed neo stop cassette was inserted into intron 1 via homologous recombination. (J:186105)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Tert Mutation:
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6 strains or lines available |
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| References |
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Original: |
J:186105
Ding Z et al.,
"Telomerase reactivation following telomere dysfunction yields murine prostate tumors with bone metastases."
Cell 2012 Mar 2;148(5):896-907
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All: |
1 reference(s)
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Analysis Tools
