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| Nomenclature |
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Symbol:
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b2b1584Clo
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Name:
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Mutant line 1584;
Bench to Bassinet Program (B2B/CVDC), mutation 1584 Cecilia Lo
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MGI ID: |
MGI:5431501 |
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Synonyms: |
Nebulous |
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Gene:
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b2b1584Clo
Location:
unknown
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Mutant 1584-004-LA displays heterotaxy indicated by dextrocardia, abnormal lung lobation and dextrogastria
Show the 12 image(s) involving this allele.
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Mutation
origin |
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Strain of Origin:
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C57BL/6J
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Mutation
description |
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Allele
Type: | |
Chemically induced (ENU) |
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Mutation: | |
Undefined |
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This ENU-induced mutation was isolated in a screen at the University of Pittsburgh.
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Notes |
Summative Diagnosis:
Laterality defects including situs inversus totalis and heterotaxia with congenital heart disease: dextrocardia, double outlet right ventricle (DORV), possible crisscross heart, and bilateral inferior vena cavae (IVC)
Noncardiac phenotype: Slow and dyskinetic airway ciliary motion
Phenotypic Similarity to Human Syndrome: Kartagener's Syndrome, Primary Ciliary Dyskinesia, Heterotaxy
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Analysis Tools