|
|
| Nomenclature |
|
Symbol:
|
b2b1167Clo
|
|
Name:
|
Mutant line 1167;
Bench to Bassinet Program (B2B/CVDC), mutation 1167 Cecilia Lo
|
|
MGI ID: |
MGI:5431499 |
|
Synonyms: |
Glow |
|
Gene:
|
b2b1167Clo
Location:
unknown
|
|
Mutant 1167-003-4 (E15.5) exhibits dextrocardia with right aortic arch, normal relative great artery positioning and mid-line liver
Show the 12 image(s) involving this allele.
|
 |
|
Mutation
origin |
|
Strain of Origin:
|
C57BL/6J
|
|
Mutation
description |
|
Allele
Type: | |
Chemically induced (ENU) |
|
Mutation: | |
Undefined |
| |
|
This ENU-induced mutation was isolated in a screen at the University of Pittsburgh.
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
|
Disease models
|
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
|
Notes |
Summative Diagnosis:
Cardiac phenotype: Laterality defects consisting of situs inversus totalis and heterotaxy with complex congenital heart disease such as dextrocardia with double outlet right ventricle (DORV) and atrioventricular canal defect (AVSD)
Noncardiac phenotype: hypoplastic spleen, right pulmonary isomerism, mid-line liver, immotile airway cilia
Phenotypic Similarity to Human Syndrome: Primary ciliary dyskinesia, Katargener's syndrome, Heterotaxy syndrome
|
Analysis Tools