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| Nomenclature |
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Symbol:
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Tg(Dyrk1a)#Jmd
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Name:
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transgene insertion, Jean M Delabar
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MGI ID: |
MGI:5430362 |
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Synonyms: |
mBACtgDyrk1A |
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Transgene:
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Tg(Dyrk1a)#Jmd
Location:
unknown
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Transgene
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:182294
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Parent Cell Line:
| D3 (ES Cell) |
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Strain of Origin:
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129S2/SvPas
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: This transgene consists of a 152 kb bacterial artificial chromosome clone, 184N10, containing the whole mouse Dyrk1a gene with a 6 kb flanking fragment on the 5' side and a 19 kb flanking fragment on the 3' side and retrofitted to containa a PGKneo cassette (184N10 BAC clone from the pBeloBac11 vector from Research Genetics). The clone contains only the Dyrk1a gene and this transgene contains one extra copy of Dyrk1a. (J:182294)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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| References |
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Original: |
J:182294
Guedj F et al.,
"DYRK1A: A master regulatory protein controlling brain growth."
Neurobiol Dis 2012 Apr;46(1):190-203
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All: |
1 reference(s)
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Analysis Tools
