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| Nomenclature |
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Symbol:
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Cdk7Gt(D032B11)1.1Wrst
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Name:
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cyclin-dependent kinase 7;
gene trap D032B11, 1.1, German Gene Trap Consortium
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MGI ID: |
MGI:5429213 |
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Synonyms: |
Cdk7lox |
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Gene:
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Cdk7
Location:
Chr13:100697027-100730942 bp, - strand
Genetic Position: Chr13,
53.23 cM
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Mutation origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:183925
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Parent Cell Line:
| TBV2 (ES Cell) |
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Strain of Origin:
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129S2/SvPas
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Mutation description |
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Allele
Type: | |
Gene trapped |
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Mutation: | |
Insertion of gene trap vector |
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Mutation details: Flp mediated recombination inverted the gene trap vector in intron 2 allowing expression of the gene. The gene trap vector has only single FRT and F3 sites. (J:183925)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:183925
Ganuza M et al.,
"Genetic inactivation of Cdk7 leads to cell cycle arrest and induces premature aging due to adult stem cell exhaustion."
EMBO J 2012 Apr 13;():
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All: |
1 reference(s)
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