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| Nomenclature |
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Symbol:
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Fcgr2btm1.2Sjv
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Name:
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Fc receptor, IgG, low affinity IIb;
targeted mutation 1.2, J Sjef Verbeek
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MGI ID: |
MGI:5427927 |
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Synonyms: |
FcgRIIBB6- |
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Gene:
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Fcgr2b
Location:
Chr1:170960558-170976547 bp, - strand
Genetic Position: Chr1,
78.02 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:179175
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Parent Cell Line:
| Bruce 4 (ES Cell) |
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Strain of Origin:
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B6.Cg-Thy1a
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: Cre-mediated recombination removed the neo cassette and exons 4 and 5. Flow cytometry confirmed the near absence of protein expression in B cells. (J:179175)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Fcgr2b Mutation:
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15 strains or lines available |
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| References |
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Original: |
J:179175
Boross P et al.,
"The inhibiting Fc receptor for IgG, FcgammaRIIB, is a modifier of autoimmune susceptibility."
J Immunol 2011 Aug 1;187(3):1304-13
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All: |
2 reference(s)
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Analysis Tools
