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| Nomenclature |
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Symbol:
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Tg(Ckm-CUGBP1)1039Coop
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Name:
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transgene insertion 1039, Thomas A Cooper
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MGI ID: |
MGI:5427873 |
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Synonyms: |
MCKCUG-BP1 |
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Transgene:
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Tg(Ckm-CUGBP1)1039Coop
Location:
unknown
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Transgene
origin |
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: A human CUGBP1, 'A' form, clone, containing an N-terminal FLAG epitope tag, was expressed in mice under the control of a mouse creatine kinase (MCK) promoter, enhancer, the untranslated exon 1, and intron 1 and bovine growth hormone 3' flanking genomic segment for proper mRNA 3' end formation. In addition to line 1039, linse 1032 and 1036 were also established. Western blot analysis showed that transgene expression is approximately 4-6 fold above endogenous levels. (J:99370)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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| References |
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Original: |
J:99370
Ho TH et al.,
"Transgenic mice expressing CUG-BP1 reproduce splicing mis-regulation observed in myotonic dystrophy."
Hum Mol Genet 2005 Jun 1;14(11):1539-47
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All: |
1 reference(s)
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Analysis Tools
