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| Nomenclature |
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Symbol:
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Smarcal1tm1.1Cfbo
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Name:
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SWI/SNF related matrix associated, actin dependent regulator of chromatin, subfamily a-like 1;
targeted mutation 1.1, Cornelius F Boerkoel
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MGI ID: |
MGI:5425295 |
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Synonyms: |
Smarcal1del |
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Gene:
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Smarcal1
Location:
Chr1:72583251-72633134 bp, + strand
Genetic Position: Chr1,
36.72 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:183899
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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129
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: A loxP site was inserted upstream of exon 2 and an FRT flanked neo cassette and loxP site were inserted downstream of exon 3 via homologous recombination. Cre mediated recombination removed exons 2 and 3 and the neo cassette. (J:183899)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Smarcal1 Mutation:
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13 strains or lines available |
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| References |
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Original: |
J:183899
Baradaran-Heravi A et al.,
"Penetrance of biallelic SMARCAL1 mutations is associated with environmental and genetic disturbances of gene expression."
Hum Mol Genet 2012 Jun 1;21(11):2572-87
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All: |
1 reference(s)
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Analysis Tools
