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| Nomenclature |
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Symbol:
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AlplMhdabap020
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Name:
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alkaline phosphatase, liver/bone/kidney;
Martin Hrabe de Angelis bone alkaline phospatase mutant 020
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MGI ID: |
MGI:5424919 |
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Synonyms: |
AlplBAP020, bone alkaline phospatase mutant 020 |
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Gene:
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Alpl
Location:
Chr4:137741733-137796384 bp, - strand
Genetic Position: Chr4,
70.02 cM
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Mutation
origin |
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Strain of Origin:
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C3HeB/FeJ
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Mutation
description |
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Allele
Type: | |
Chemically induced (ENU) |
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Mutation: | |
Single point mutation |
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Mutation details: This ENU-induced mutation was isolated in a screen for metabolic bone disease as part of the Munich ENU Mutagenesis Project. Synonymous sequence variation in exon 10 of the gene; an A-to-T point mutation at position 1098 of the cDNA is predicted to alter codon 365 in the encoded protein. (J:183993)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:183993
Sabrautzki S et al.,
"New mouse models for metabolic bone diseases generated by genome-wide ENU mutagenesis."
Mamm Genome 2012 Aug;23(7-8):416-30
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All: |
1 reference(s)
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Analysis Tools
