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| Nomenclature |
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Symbol:
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Gt(ROSA)26Sortm1(Thy1-FBXL2)Wata
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Name:
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gene trap ROSA 26, Philippe Soriano;
targeted mutation 1, Tomomichi Watanabe
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MGI ID: |
MGI:5318566 |
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Gene:
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Gt(ROSA)26Sor
Location:
Chr6:113067428-113077333 bp, - strand
Genetic Position: Chr6,
52.73 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:182731
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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C57BL/6N
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Mutation
description |
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Allele
Type: | |
Targeted (knock-in) |
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Mutation: | |
Insertion |
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Mutation details: The expression cassette was knocked into the locus. This vector contains a splice acceptor, ATG start codon, neo cassette, polyadenylation sequence, 5' Thy1 promoter region, human open reading frame, and 3' Thy1 promoter region. (J:182731)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Gt(ROSA)26Sor Mutation:
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197 strains or lines available |
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| References |
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Original: |
J:182731
Watanabe T et al.,
"FBL2 regulates amyloid precursor protein (APP) metabolism by promoting ubiquitination-dependent APP degradation and inhibition of APP endocytosis."
J Neurosci 2012 Mar 7;32(10):3352-65
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All: |
1 reference(s)
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Analysis Tools
