|
|
| Nomenclature |
|
Symbol:
|
Slc12a6tm1Garo
|
|
Name:
|
solute carrier family 12, member 6;
targeted mutation 1, Guy A Rouleau
|
|
MGI ID: |
MGI:5318538 |
|
Synonyms: |
Slc12a6flox |
|
Gene:
|
Slc12a6
Location:
Chr2:112265825-112363163 bp, + strand
Genetic Position: Chr2,
56.99 cM
|
|
Mutation
origin |
|
Germline Transmission:
|
Earliest citation of germline transmission:
J:183239
|
|
Parent Cell Line:
| Not Specified (ES Cell) |
|
Strain of Origin:
|
129
|
|
Mutation
description |
|
Allele
Type: | |
Targeted (Floxed/Frt) |
|
Mutation: | |
Insertion |
| |
|
Mutation details: An FRT and LoxP flanked neo cassette was inserted upstream of exon 18 and a loxP site was inserted downstream of exon 18 via homologous recombination. (J:183239)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
|
Disease models
|
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
| References |
|
Original: |
J:183239
Shekarabi M et al.,
"Loss of neuronal potassium/chloride cotransporter 3 (KCC3) is responsible for the degenerative phenotype in a conditional mouse model of hereditary motor and sensory neuropathy associated with agenesis of the corpus callosum."
J Neurosci 2012 Mar 14;32(11):3865-76
|
|
All: |
1 reference(s)
|
|
Analysis Tools
