|
|
| Nomenclature |
|
Symbol:
|
Slamf6tm1Pls
|
|
Name:
|
SLAM family member 6;
targeted mutation 1, Pamela L Schwartzberg
|
|
MGI ID: |
MGI:5318529 |
|
Synonyms: |
Ly108- |
|
Gene:
|
Slamf6
Location:
Chr1:171917537-171943868 bp, + strand
Genetic Position: Chr1,
79.54 cM
|
|
Mutation origin |
|
Germline Transmission:
|
Earliest citation of germline transmission:
J:183088
|
|
Parent Cell Line:
| Other (see notes) (ES Cell) |
|
Strain of Origin:
|
C57BL/6J
|
|
Mutation description |
|
Allele
Type: | |
Targeted (knock-out) |
|
Mutation: | |
Insertion |
| |
|
Mutation details: A stop codon was introduced into exon 2 and replaced part of exons 2 and 3 with a neo cassette. Flow cytometry confirmed the absence of protein expression. (J:183088, J:193308)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
|
Carrying any Slamf6 Mutation:
|
3 strains or lines available |
|
|
Notes |
ES cell line = HGTC-8 (C57BL/6J)
|
| References |
|
Original: |
J:183088
Dutta M et al.,
"Characterization of Ly108 in the thymus: evidence for distinct properties of a novel form of Ly108."
J Immunol 2012 Apr 1;188(7):3031-41
|
|
All: |
3 reference(s)
|
|