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| Nomenclature |
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Symbol:
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Gt(ROSA)26Sortm1.1(CAG-COX8A/Dendra2)Dcc
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Name:
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gene trap ROSA 26, Philippe Soriano;
targeted mutation 1.1, David C Chan
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MGI ID: |
MGI:5318241 |
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Synonyms: |
Gt(ROSA)26Sortm1.1(CAG-Mito-Dendra2)Dcc, mito-Dendra2, PhAMexcised |
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Gene:
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Gt(ROSA)26Sor
Location:
Chr6:113067428-113077333 bp, - strand
Genetic Position: Chr6,
52.73 cM
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Mutation origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:183305
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Parent Cell Line:
| TC1/TC-1 (ES Cell) |
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Strain of Origin:
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129S6/SvEvTac
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Mutation description |
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Allele
Type: | |
Targeted (Reporter) |
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Mutation: | |
Insertion |
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Mutation details: Dendra2 (a green to red irreversibly photoswitchable monomeric fluorescent protein derived from octocoral Dendronephthya sp.) fused to the mitochondrial targeting signal of subunit VIII of cytochrome c oxidase (mito-Dendra2), bovine growth hormone (bGH) polyadenylation signal, and an FRT-flanked neomycin cassette were introduced to Gt(ROSA)26Sor downstream of a CAG (CMV-beta-actin) promoter and loxP-flanked termination signal. Flp-mediated recombination removed the neo cassette. (J:183306, J:189358)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:183306
Chan DC,
"Direct Data Submission 2012/05/14"
MGI Direct Data Submission 2012;():
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All: |
4 reference(s)
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