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| Nomenclature |
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Symbol:
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Ifngtm3.1Lky
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Name:
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interferon gamma;
targeted mutation 3.1, Richard M Locksley
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MGI ID: |
MGI:5317415 |
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Synonyms: |
GREAT, Ifngtm3(EYFP)Lky |
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Gene:
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Ifng
Location:
Chr10:118441047-118445892 bp, + strand
Genetic Position: Chr10,
66.75 cM
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Mutation origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:147784
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Parent Cell Line:
| PC3 (ES Cell) |
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Strain of Origin:
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129S4/SvJae-Tg(Prm-cre)70Og
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Mutation description |
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Allele
Type: | |
Targeted (Reporter) |
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Mutation: | |
Insertion |
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Mutation details: A targeting vector was designed with a loxP-flanked neomycin resistance cassette, an internal ribosome entry site (IRES), and an enhanced yellow fluorescent protein (eYFP) sequence. This vector was inserted downstream of the endogenous translational stop codon and upstream of the 3' untranslated region (UTR). Cre-mediated recombination removed the neo cassette. (J:147784)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Notes |
Smart (Surface marker for transcription)-17A
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| References |
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Original: |
J:147784
Reinhardt RL et al.,
"Cytokine-secreting follicular T cells shape the antibody repertoire."
Nat Immunol 2009 Apr;10(4):385-93
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All: |
3 reference(s)
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