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| Nomenclature |
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Symbol:
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Tg(PAX6)77Ndha
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Name:
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transgene insertion 77, Nicholas Hastie
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MGI ID: |
MGI:5316840 |
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Synonyms: |
PAX6YAC, PAX77 |
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Transgene:
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Tg(PAX6)77Ndha
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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(CBA x C57BL/6)F1
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: The centromeric arme of YAC Y593 (human ICI library) was replaced with an amplifiable vector by homologous recombination in yeast before injection into fertilized mouse oocytes. Five to seven opies were inserted in this line. Additional lines produced include PAX88 and PAX130 (both with two copies) and PAX138 (with 10 copies). (J:34194)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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| References |
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Original: |
J:34194
Schedl A et al.,
"Influence of PAX6 gene dosage on development: overexpression causes severe eye abnormalities."
Cell 1996 Jul 12;86(1):71-82
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All: |
4 reference(s)
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Analysis Tools
