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| Nomenclature |
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Symbol:
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Tg(ACTA1*D286G/EGFP)#Kjno
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Name:
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transgene insertion, Kristen J Nowak
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MGI ID: |
MGI:5316719 |
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Synonyms: |
Tg(ACTA1.D286G-EGFP), Tg(ACTA1)D286G-EGFP |
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Transgene:
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Tg(ACTA1*D286G/EGFP)#Kjno
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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C57BL/6J x CBA/Ca
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: This transgene expresses the human ACTA1 protein containing the D286G mutation fused at the C terminus to the coding sequence for EGFP under the control of the human skeletal muscle alpha-actin promoter (ACTA1) and the troponin-I slow upstream enhancer. The pound symbol (#) is used when line is not specified and/or lines are pooled. (J:182255)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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| References |
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Original: |
J:182255
Ravenscroft G et al.,
"Actin nemaline myopathy mouse reproduces disease, suggests other actin disease phenotypes and provides cautionary note on muscle transgene expression."
PLoS One 2011;6(12):e28699
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All: |
1 reference(s)
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Analysis Tools
