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| Nomenclature |
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Symbol:
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Slc12a5tm2.1Tjj
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Name:
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solute carrier family 12, member 5;
targeted mutation 2.1, Thomas J Jentsch
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MGI ID: |
MGI:5315721 |
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Synonyms: |
Kcc2loxP |
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Gene:
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Slc12a5
Location:
Chr2:164960816-164999727 bp, + strand
Genetic Position: Chr2,
85.28 cM, cytoband G2-G3
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:181930
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Parent Cell Line:
| R1 (ES Cell) |
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Strain of Origin:
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(129X1/SvJ x 129S1/Sv)F1-Kitl+
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: A floxed neo cassette was inserted into intron 1. An additional loxP site was inserted into intron 5. Cre-mediated recombination removed the neo cassette and left exons 2 through 5 floxed. (J:181930)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Slc12a5 Mutation:
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1 strain or line available |
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| References |
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Original: |
J:181930
Seja P et al.,
"Raising cytosolic Cl(-) in cerebellar granule cells affects their excitability and vestibulo-ocular learning."
EMBO J 2012 Mar 7;31(5):1217-30
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All: |
1 reference(s)
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Analysis Tools
