Wnt7apx-J
Spontaneous Allele Detail
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| Nomenclature |
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Symbol:
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Wnt7apx-J
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Name:
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wingless-related MMTV integration site 7A;
postaxial hemimelia Jackson
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MGI ID: |
MGI:5315307 |
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Gene:
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Wnt7a
Location:
Chr6:91363981-91411363 bp, - strand
Genetic Position: Chr6,
40.45 cM
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Mutation
origin |
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Strain of Origin:
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C57BL/6J
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Mutation
description |
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Allele
Type: | |
Spontaneous |
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Mutations: | |
Deletion, Single point mutation |
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Mutation details: This spontaneous mutation in Chromosome 6 has a G to A transition at 91,344,546 (NCBI37/mm9) causing the replacement of arginine with tryptophan at amino acid 143, and also has a 23,106 bp intragenic deletion, 91,321,380 - 91,244,486, that encompasses a portion of exon 3 and removes the 5' end of intron 3 including the splice donor site. (J:188477)
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Inheritance: | |
Recessive |
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:188477
Dionne L et al.,
"Postaxial hemimelia Jackson, a new spontaneous mouse mutation in Wnt7a"
MGI Direct Data Submission 2012;():
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All: |
1 reference(s)
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Analysis Tools
