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| Nomenclature |
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Symbol:
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Tg(Myh6-Actc1*R312H)307Iko
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Name:
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transgene insertion 307, Issei Komuro
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MGI ID: |
MGI:5313511 |
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Transgene:
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Tg(Myh6-Actc1*R312H)307Iko
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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C57BL/6
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: This transgene expresses the mouse cardiac alpha-actin with a histidine substitution for an arginine at amino acid 312 (R312H) and an HA tag under the control of the murine alpha-myosin heavy chain promoter. Three lines were made, with line 307 the highest expressor. (J:178587)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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| References |
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Original: |
J:178587
Toko H et al.,
"Ca2+/calmodulin-dependent kinase IIdelta causes heart failure by accumulation of p53 in dilated cardiomyopathy."
Circulation 2010 Aug 31;122(9):891-9
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All: |
1 reference(s)
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Analysis Tools
