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| Nomenclature |
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Symbol:
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Xpatm1Gvh
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Name:
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xeroderma pigmentosum, complementation group A;
targeted mutation 1, Gijsbertus T J van der Horst
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MGI ID: |
MGI:5312129 |
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Synonyms: |
Xpac |
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Gene:
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Xpa
Location:
Chr4:46155347-46196311 bp, - strand
Genetic Position: Chr4,
24.49 cM, cytoband C2
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Ercc6tm1Gvh/Ercc6tm1Gvh Xpatm1Gvh/Xpatm1Hvs Tg(CAG-cre)13Miya/0 mice are severely reduced in size
Show the 6 image(s) involving this allele.
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:179808
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Parent Cell Line:
| IB10/E14IB10 (ES Cell) |
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Strain of Origin:
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129P2/OlaHsd
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: A construct replaced exon 4. This construct contains (5' to 3'): loxP, cDNA encoding exons 4-6, hygro, loxP, splice acceptor, Murfi cassette, IRES, lacZ and GFP. (J:179808)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Xpa Mutation:
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7 strains or lines available |
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| References |
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Original: |
J:179808
Jaarsma D et al.,
"Age-related neuronal degeneration: complementary roles of nucleotide excision repair and transcription-coupled repair in preventing neuropathology."
PLoS Genet 2011 Dec;7(12):e1002405
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All: |
1 reference(s)
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Analysis Tools
