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| Nomenclature |
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Symbol:
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Tg(Thy1-TARDBP*G298S)S97Pcw
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Name:
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transgene insertion S97, Philip C Won
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MGI ID: |
MGI:5308398 |
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Transgene:
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Tg(Thy1-TARDBP*G298S)S97Pcw
Location:
unknown
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Transgene origin |
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Strain of Origin:
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(C57BL/6 x SJL)F1
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Transgene description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: This transgene contains the mouse Thy1 (thymus cell antigen 1, theta, promoter (Thy1.2)) promoter driving expression of the full-length human TAR DNA binding protein (TARDBP) cDNA sequence. A missense mutation associated with amyotrophic lateral sclerosis (ALS) was introduced at position 298 results in a glycine-to-serine substitution (G298S). Line S97 was established. (J:180948)
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:180948
Won PC,
"Direct Data Submission 2012/03/02"
MGI Direct Data Submission 2012;():
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All: |
1 reference(s)
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