|
|
| Nomenclature |
|
Symbol:
|
Pomt2tm1.1Hhu
|
|
Name:
|
protein-O-mannosyltransferase 2;
targeted mutation 1.1, Huaiyu Hu
|
|
MGI ID: |
MGI:5302103 |
|
Gene:
|
Pomt2
Location:
Chr12:87106866-87147902 bp, - strand
Genetic Position: Chr12,
41.3 cM
|
|
Mutation
origin |
|
Germline Transmission:
|
Earliest citation of germline transmission:
J:179356
|
|
Parent Cell Line:
| Other (see notes) (ES Cell) |
|
Strain of Origin:
|
(129S6/SvEvTac x C57BL/6J)F1
|
|
Mutation
description |
|
Allele
Type: | |
Targeted (Floxed/Frt) |
|
Mutation: | |
Insertion |
| |
|
Mutation details: An FRT-flanked neo cassette with a 5' loxP site was inserted upstream of exon 2. An additional loxP site was inserted downstream of exon 4. Flp-mediated recombination removed the neo cassette and left exons 2 through 4 floxed. (J:179356)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
|
Notes |
ES cell line = D2 (129S6/SvEvTac x C57BL/6J)F1
|
| References |
|
Original: |
J:179356
Hu H et al.,
"Conditional knockout of protein O-mannosyltransferase 2 reveals tissue-specific roles of O-mannosyl glycosylation in brain development."
J Comp Neurol 2011 May 1;519(7):1320-37
|
|
All: |
2 reference(s)
|
|
Analysis Tools
