Foxj1<b2b774Clo> Chemically induced Allele Detail MGI Mouse (MGI:5297425)

Foxj1^b2b774Clo
Chemically induced Allele Detail

Nomenclature

Symbol:	Foxj1^b2b774Clo
Name:	forkhead box J1; Bench to Bassinet Program (B2B/CVDC), mutation 774 Cecilia Lo
MGI ID:	MGI:5297425
Synonyms:	Foxj1^T425A, Tails
Gene:	Foxj1 Location: Chr11:116330704-116335399 bp, - strand Genetic Position: Chr11, 81.16 cM

Situs inversus totalis indicated by dextrocardia and dextrogastria

Show the 4 image(s) involving this allele.

Mutation
origin

Strain of Origin:

C57BL/6J

Mutation
description

Allele Type:		Chemically induced (ENU)
Mutation:		Single point mutation
		This ENU-induced mutation was isolated in a screen at the University of Pittsburgh. (J:175213)

Phenotypes

View phenotypes for all genotypes (concatenated display).

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)

Carrying this Mutation:	Mouse Strains: 1 strain available Cell Lines: 0 lines available
Carrying any Foxj1 Mutation:	2 strains or lines available

Notes

Summative Diagnosis:
Laterality defects: Situs inversus totalis and heterotaxy

Fyler Codes
The Fyler code developed by The Boston Children's Heart Foundation in Boston Children's Hospital provides a hierarchical clinical diagnosis of congenital cardiovascular defects and other disorders. These codes are used to delineate pathology in the mutant mouse models that parallel human disease and can be cross referenced to the International Pediatric and Congenital Cardiac Code (IPCCC) (http://www.ipccc.net/).

Fyler Code ID	Code Description
0100	Situs inversus totalis
3608	Left ventricular hypertrophy
3609	Right ventricular hypertrophy
3974	{I,L,I}

References

Original:	J:175213 Lo C, "Information submitted by the NHLBI Cardiovascular Development Consortium (CvDC), Bench to Bassinet Program" MGI Direct Data Submission (B2B/CvDC) 2011;():
All:	1 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources Funding Information Warranty Disclaimer & Copyright Notice Send questions and comments to User Support.	last database update 05/08/2013 MGI 5.13