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| Nomenclature |
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Symbol:
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Mapk1tm1.2Kuta
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Name:
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mitogen-activated protein kinase 1;
targeted mutation 1.2, Kunio Takishima
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MGI ID: |
MGI:5293422 |
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Synonyms: |
ERK2fl, Erk2flox(Neo-) |
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Gene:
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Mapk1
Location:
Chr16:16983382-17047453 bp, + strand
Genetic Position: Chr16,
10.53 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:171965
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Parent Cell Line:
| E14 (ES Cell) |
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Strain of Origin:
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129P2/OlaHsd
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: A floxed PGK-neo cassette was inserted in reverse direction into intron 1 and an additional loxP site was inserted into intron 3. Cre mediated recombination removed the neo cassette. (J:125594, J:176051)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Mapk1 Mutation:
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20 strains or lines available |
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| References |
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Original: |
J:171965
Imamura O et al.,
"Analysis of extracellular signal-regulated kinase 2 function in neural stem/progenitor cells via nervous system-specific gene disruption."
Stem Cells 2008 Dec;26(12):3247-56
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All: |
6 reference(s)
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Analysis Tools
