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| Nomenclature |
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Symbol:
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Slc6a19tm1Dgen
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Name:
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solute carrier family 6 (neurotransmitter transporter), member 19;
targeted mutation 1, Deltagen
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MGI ID: |
MGI:5288516 |
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Gene:
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Slc6a19
Location:
Chr13:73679745-73704865 bp, - strand
Genetic Position: Chr13,
40.14 cM, cytoband C1
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Decreased body weight in Slc6a19tm1Dgen mice
Show the 1 image(s) involving this allele.
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:175382
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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129
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Mutation
description |
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Allele
Type: | |
Targeted (Reporter) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: Exon 3 was replaced with a lacZ-neo cassette. The absence of protein expression was confirmed by western blot analysis on small intestine and kidney extracts. (J:175382)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Slc6a19 Mutation:
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2 strains or lines available |
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| References |
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Original: |
J:175382
Broer A et al.,
"Impaired nutrient signaling and body weight control in a Na+ neutral amino acid cotransporter (Slc6a19)-deficient mouse."
J Biol Chem 2011 Jul 29;286(30):26638-51
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All: |
1 reference(s)
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Analysis Tools
